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Alpha 2 Macroglobulin

joint pain

Alpha 2 Macroglobulin


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As we learn more about pain and the factors which contribute to pain, it becomes clear how important regenerative medicine techniques are going to be within the future of healthcare. At Remedy Pain Solutions, we pride ourselves on utilizing some of the most advanced and effective regenerative techniques available. One regenerative medicine technique becoming an integral part of our practice is Alpha 2 Macroglobulin, or A2M injection therapy. 


Alpha 2 Macroglobulin is a plasma protein found in the blood which functions as a “protease inhibitor.” Proteases are enzymes that cause damage and breakdown of certain proteins found in the body. More specifically, the proteases inhibited by A2M are those known to break down joint cartilage, and are present in large numbers following joint injury. Inhibiting these damaging proteases encourages the body’s natural healing properties to overcome localized areas of disease, pain, or slow healing, and effectively restore the affected joint or body part. 


The process of acquiring A2M is very similar to that of Platelet-Rich Plasms (PRP) collection, another regenerative therapy performed at Remedy Pain Solutions. A provider will collect a sample of blood from the patient which is then placed in a centrifuge, spinning the blood and quickly separating it into its multiple components. The blood is then processed through a system of filtration, after which a concentrated volume of A2M remains. This can be safely and easily performed within the comfort of our procedure suite at Remedy Pain Solutions in Marina Del Rey. Unlike PRP which induces an inflammatory response upon injection, A2M injections are actually able to avoid inducing inflammation through the process of protease inhibition. By avoiding the usual post-procedural inflammation which is expected with other regenerative therapies, A2M injections will rarely cause any significant pain following the procedures. 


At Remedy Pain Solutions we are proud to offer A2M injection therapy to our patients, providing a safe and effective solution to joint pain and degradation. If you are living near Marina Del Rey, California and are suffering with pain in one or multiple joints, come in to Remedy Pain Solutions where we’ll be happy to discuss whether Alpha 2 Macroglobulin injections are the right choice for you.

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